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Bio-electrochemistry of P450’s

A typical electrochemical signal is shown below where the cyclic voltammetry showing the reactivity of the P450 heam iron

A typical electrochemical signal

and its catalytic current in the presence of a substrate is shown.

catalytic current in the presence of a substrate

A typical time-course of an experiment where a substrate is titrated into the P450-electrode well is shown in the figure below where the construction of a Michaelis Menten curve is also displayed.

Michaelis Menten curve

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